A PEER-REVIEWED JOURNAL OF RESEARCH AND CLINICAL MEDICINEISSN 1727-2378 (Print)         ISSN 2713-2994 (Online)
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Management of a Patient with Gastric Cancer During Pregnancy

DOI:10.31550/1727-2378-2020-19-1-21-24
For citation: Protasova A.E., Zazerskaya I.E., Ilyin A.B., Osipova N.A., Shelepova E.S., Bobrova E.A. Management of a Patient with Gastric Cancer During Pregnancy. Doctor.Ru. 2020; 19(1): 21–24. (in Russian) DOI: 10.31550/1727-2378-2020-19-1-21-24

Study Objective. To present a case of a pregnant woman with gastric cancer (GC); to focus on diagnostic search and treatment strategy.

Key Points. A 22-year old patient(N.) was diagnosed with GC сT3NxM0 G3, HER-2/neu negative at gestation week 33 2/7. Taking into account GC (colloid morphologic variant), duration of gestation guaranteeing viable foetus, it was decided to perform caesarean section. On day 5 postpartum, the patient was transferred to the oncology centre for treatment and induction (preoperative) poly chemotherapy. The patient underwent two cycles of chemotherapy (standard FLOT regimen) with partial regression. Then, extended gastrectomy with lymph node dissection D2 was undertaken, followed by three cycles of postoperative chemotherapy using the same regimen.

Conclusion. Management approach for pregnant patients with cancer should be multidisciplinary, involving obstetrician/ gynaecologist and oncologist who possess adequate clinical experience and state-of-art knowledge. It will allow to timely define the therapy strategy, time and type of delivery, taking into account duration of gestation, disease state and minimisation of risks for mother and foetus.

Conflict of interest: the authors declare no potential conflicts of interests.

Received: 25.09.2019
Accepted: 11.12.2019

A.E. Protasova (Corresponding author) — V.A. Almazov National Medical Research Center; 2 Akkuratova Str., St. Petersburg, Russian Federation 197341. eLIBRARY.RU SPIN: 4097-0969. E-mail: protasova1966@yandex.ru

I.E. Zazerskaya — V.A. Almazov National Medical Research Center; 2 Akkuratova Str., St. Petersburg, Russian Federation 197341. eLIBRARY.RU SPIN: 5683-6741. E -mail: zazera@mail.ru

A.B. Ilyin — V.A. Almazov National Medical Research Center; 2 Akkuratova Str., St. Petersburg, Russian Federation 197341. E-mail: a-ilyin@inbox.ru

N.A. Osipova — V.A. Almazov National Medical Research Center; 2 Akkuratova Str., St. Petersburg, Russian Federation 197341. eLIBRARY.RU SPIN: 6151-8696. E-mail: naosipova@mail.ru

E.S. Shelepova — V.A. Almazov National Medical Research Center; 2 Akkuratova Str., St. Petersburg, Russian Federation 197341. eLIBRARY.RU SPIN: 9474-1351. E-mail: shelepowa@gmail.com

E.A. Bobrova — V.A. Almazov National Medical Research Center; 2 Akkuratova Str., St. Petersburg, Russian Federation 197341. E-mail: dr.bobrovavma@gmail.com

Доктор.ру

Fig. Abdomen MRI Gastric paraplasm (red arrow). Image: Courtesy of the authors

ris4_1.jpg

LITERATURE
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