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Nervous System Functioning in Pregnant Women with Postconcussion Syndrome

Bibliography link: Simrok V. V., Tsyganenko I. V. Nervous System Functioning in Pregnant Women with Postconcussion Syndrome. Doctor.Ru. 2017; 13(142)—14(143): 62–65.
Nervous System Functioning in Pregnant Women with Postconcussion Syndrome
19 December 00:00

Study Objective: To study nervous system functioning in pregnant women with postconcussion syndrome (PCS) following mild closed traumatic brain injury and to assess the effects of this syndrome on obstetric outcomes.

Study Design: This was an observational case-control study.

Materials and Methods: One hundred and nineteen women were examined in the study. The main group (MG) consisted of 67 pregnant women with PCS following mild closed traumatic brain injury; the comparison group (ComG) was made up of 32 non-pregnant women with PCS, and the control group (ConG) was comprised of 20 pregnant women without somatic disorders. The intensity of symptoms and cognitive and psychovegetative impairments was assessed by a modified version of the Post-Concussion Symptom Scale developed by M. R. Lovell et al. Neuropsychological status of the pregnant women with PCS was assessed on weeks 12 and 23 of pregnancy.

Study Results: In main group patients neuropsychological status started to deteriorate at week 23 of pregnancy: headache became more intense, headache and sleep problems became more frequent, irritability, nervousness, and occasional palpitations were reported more often, and general malaise and emotional lability became more marked. The following neurological syndromes were the most commonly observed components of PCS in the MG and ComG, respectively: autonomic dysfunction (32.72% and 34.38%), cephalgia (21.84% and 25.00%), cognitive impairments (19.54% and 18.75%), asthenia (12.54% and 15.63%), and vestibular dysfunction (2.37% and 6.25%).

In the MG the frequency of fetoplacental dysfunction, intrauterine growth retardation, and hypertensive disorders during pregnancy was greater (3.6, 4.6, and 2.8 times, respectively) than in the ConG. In the MG preterm deliveries occurred 2.8 times more often, and cesarean section was performed 2.5 times more frequently than in the ConG.

Conclusion: Pregnancy and PCS are mutually exacerbating conditions, which requires further investigation of their common pathogenic pathways underlying obstetric and neurological complications. This will help develop preventive, therapeutic, and obstetric strategies for pregnant women with post-head injury neurological disorders.

V. V. Simrok — St. Luka Lugansk State Medical University. E-mail: partus7@yandex.ru

I. V. Tsyganenko — St. Luka Lugansk State Medical University. E-mail: kosenkoira@list.ru

Nervous System Functioning in Pregnant Women with Postconcussion Syndrome
19 December 00:00
LITERATURE
  1. Мументалер М., Бассетти К., Дэтвайлер К. Дифференциальный диагноз в неврологии. Руководство по оценке, классификации и дифференциальной диагностике неврологических симптомов. М.: МЕДпресс-информ; 2010. 350 с. [Mumentaler M., Bassetti K., Detvailer K. Differentsial'nyi diagnoz v nevrologii. Rukovodstvo po otsenke, klassifikatsii i differentsial'noi diagnostike nevrologicheskikh simptomov. M.: MEDpress-inform; 2010. 350 s. (in Russian)]
  2. Лихтерман Л. Б., Кравчук А. Д., Филатова М. М.. Сотрясение головного мозга: тактика лечения и исходы. Клин. неврология. 2008; 2(1): 12–21. [Likhterman L. B., Kravchuk A. D., Filatova M. M.. Sotryasenie golovnogo mozga: taktika lecheniya i iskhody. Klin. nevrologiya. 2008; 2(1): 12–21. (in Russian)]
  3. Вышлова И. А., Карпов С. М., Апагуни А. Э., Стародубцев А. И. Последствия легкой черепно-мозговой травмы (обзорная статья). Междунар. журн. эксперим. образования. 2014; 5-1: 27–31. [Vyshlova I. A., Karpov S. M., Apaguni A. E., Starodubtsev A. I. Posledstviya legkoi cherepno-mozgovoi travmy (obzornaya stat'ya). Mezhdunar. zhurn. eksperim. obrazovaniya. 2014; 5-1: 27–31. (in Russian)]
  4. Организация специализированной нейрореабилитационной помощи больным с очаговыми поражениями головного мозга в результате инсульта, черепно-мозговой травмы и других заболеваний центральной нервной системы. Методическое письмо 06.02.2016. http://www.insult.ru/metod.php (дата обращения — 15.10.2017). [Organizatsiya spetsializirovannoi neiroreabilitatsionnoi pomoshchi bol'nym s ochagovymi porazheniyami golovnogo mozga v rezul'tate insul'ta, cherepno-mozgovoi travmy i drugikh zabolevanii tsentral'noi nervnoi sistemy. Metodicheskoe pis'mo 06.02.2016. http://www.insult.ru/metod.php (data obrashcheniya — 15.10.2017). (in Russian)]
  5. Вейн А. М. Лекции по неврологии неспецифических систем мозга. М.: МЕДпресс-информ; 2010. 112 с. [Vein A. M. Lektsii po nevrologii nespetsificheskikh sistem mozga. M.: MEDpress-inform; 2010. 112 s. (in Russian)]
  6. Постконтузионный синдром. МКБ-10. http://mkb-10.com/index.php?pid = 4043 (дата обращения — 15.10.2017). [Postkontuzionnyi sindrom. MKB-10. http://mkb-10.com/index.php?pid = 4043 (data obrashcheniya — 15.10.2017). (in Russian)]
  7. Мироненко Т. В., Симрок В. В., Мироненко М. О., Симрок-Старчева Д. В. Вагітність і пологи при захворюваннях центральної і периферичної нервової системи (керівництво для лікарів). Луганськ; 2010. 84 с. [Mironenko T. V., Simrok V. V., Mironenko M. O., Simrok-Starcheva D. V. Vagіtnіst' і pologi pri zakhvoryuvannyakh tsentral'noї і periferichnoї nervovoї sistemi (kerіvnitstvo dlya lіkarіv). Lugans'k; 2010. 84 s. (in Ukrainian)]
  8. Sinha S., Gunawat P., Nehra A., Sharma B. Cognitive, functional, and psychosocial outcome after severe traumatic brain injury: a cross-sectional study at a tertiary care trauma center. Neurol. India. 2013; 61(5): 42–5.
  9. Волынкин А. А., Власов П. Н., Петрухин В. А., Ахвледиани К. Н. Психический статус у беременных с последствиями черепно-мозговой травмы. Неврология, нейропсихиатрия, психосоматика. 2017; 9(2): 36–9. [Volynkin A. A., Vlasov P. N., Petrukhin V. A., Akhvlediani K. N. Psikhicheskii status u beremennykh s posledstviyami cherepno-mozgovoi travmy. Nevrologiya, neiropsikhiatriya, psikhosomatika. 2017; 9(2): 36–9. (in Russian)]
  10. Краснопольский В. И., Петрухин В. А., Ахвледиани К. Н., Волынкин А. А., Власов П. Н. Родоразрешение беременных с последствиями черепно-мозговой травмы. Доктор.Ру. 2016; 7(124): 57–60. [Krasnopol'skii V. I., Petrukhin V. A., Akhvlediani K. N., Volynkin A. A., Vlasov P. N. Rodorazreshenie beremennykh s posledstviyami cherepno-mozgovoi travmy. Doktor.Ru. 2016; 7(124): 57–60. (in Russian)]
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