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The Hormonal Status of Female Patients of Reproductive Age with Chronic Cystitis and Undifferentiated Connective Tissue Dysplasia

Bibliography link: Moskovenko N. V., Beznoshchenko G. B., Andryukhin M. I. The Hormonal Status of Female Patients of Reproductive Age with Chronic Cystitis and Undifferentiated Connective Tissue Dysplasia. Doctor.Ru. 2017; 7(136): 46–50.
The Hormonal Status of Female Patients of Reproductive Age with Chronic Cystitis and Undifferentiated Connective Tissue Dysplasia
20 July 00:00

Study Objective: To study the hormonal status of female patients of reproductive age with chronic cystitis and undifferentiated connective tissue dysplasia (UCTD).

Study Design: This was a prospective cohort study.

Materials and Methods: Six hundred and fifteen female chronic cystitis patients were examined in the study. The following parameters were measured: luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin, estradiol, progesterone, cortisol, and thyroid-stimulating hormone (TSH). The women were examined for clinical signs of UCTD, and connective-tissue metabolism markers were assessed. Urination disorders were assessed by the International Prostate Symptom Score. Other study methods included combined urodynamic testing and urethrocystoscopy with biopsy.

Study Results: The examination revealed a high prevalence of gynecological disorders, mostly of inflammatory origin. UCTD was diagnosed in 73.5% women; the frequency of urination disorders was significantly higher in these women. Women in the study cohort tended to have lower levels of estradiol and higher levels of TSH, prolactin, and cortisol. They also had various changes in the bladder wall, which were most significant in women with UCTD.

Conclusion: Low estradiol levels and UCTD are significant factors in the nature of inflammatory changes in the bladder wall. It would be logical to suggest that in women of reproductive age, recurrent cystitis can be effectively treated only if they receive appropriate treatment for hormonal imbalances and timely care for their gynecological comorbidities.

N. V. Moskovenko — Omsk State Medical University. City Hospital No. 2, Omsk. E-mail: moskowenko-natalya@yandex.ru

G. B. Beznoshchenko — Omsk State Medical University. E-mail: reсtor@omsk-osma.ru

M. I. Andryukhin — Peoples’ Friendship University of Russia, Moscow. E-mail: rector@rudn.ru

The Hormonal Status of Female Patients of Reproductive Age with Chronic Cystitis and Undifferentiated Connective Tissue Dysplasia
20 July 00:00
LITERATURE
  1. Ибишев Х. С. Некоторые аспекты лечения персистирующей инфекции нижних мочевыводящих путей у женщин. Урология. 2014; 5: 30–4. [Ibishev Kh. S. Nekotorye aspekty lecheniya persistiruyushchei infektsii nizhnikh mochevyvodyashchikh putei u zhenshchin. Urologiya. 2014; 5: 30–4. (in Russian)]
  2. Лоран О. Б., Писарев С. А. Морфологическая характеристика гиперактивности мочевого пузыря. Consilium Medicum. Экстра-выпуск. М.: Media Medica; 2006: 5. [Loran O. B., Pisarev S. A. Morfologicheskaya kharakteristika giperaktivnosti mochevogo puzyrya. Consilium Medicum. Ekstravypusk. M.: Media Medica; 2006: 5. (in Russian)]
  3. Неймарк А. И., Раздольская М. В., Сизов К. А. Коррекция нарушений микроциркуляции в стенке мочевого пузыря. Казанский мед. журн. 2012; 93(1): 48–52. [Neimark A. I., Razdol'skaya M. V., Sizov K. A. Korrektsiya narushenii mikrotsirkulyatsii v stenke mochevogo puzyrya. Kazanskii med. zhurn. 2012; 93(1): 48–52. (in Russian)]
  4. Перепанова Т. С., Ганковская Л. В., Волкова Е. М., Свитич О. А., Греченко В. В., Беренштейн А. В. Состояние врожденного иммунитета слизистых оболочек у пациенток с рецидивирующим бактериальным циститом. Урология. 2014; 4: 30–2. [Perepanova T. S., Gankovskaya L. V., Volkova E. M., Svitich O. A., Grechenko V. V., Berenshtein A. V. Sostoyanie vrozhdennogo immuniteta slizistykh obolochek u patsientok s retsidiviruyushchim bakterial'nym tsistitom. Urologiya. 2014; 4: 30–2. (in Russian)]
  5. Котенко А. А., Смелышева Л. Н., Котенко И. Н. Особенности вегетативной и гормональной регуляции у женщин с синдромом гиперактивного мочевого пузыря. Урология. 2015; 3: 24–8. [Kotenko A. A., Smelysheva L. N., Kotenko I. N. Osobennosti vegetativnoi i gormonal'noi regulyatsii u zhenshchin s sindromom giperaktivnogo mochevogo puzyrya. Urologiya. 2015; 3: 24–8. (in Russian)]
  6. Кульчавеня Е. В., Брижатюк Е. В., Хомяков В. Т. Частота возникновения цистита в зависимости от вида контрацепции. Урология. 2013; 1: 41–3. [Kul'chavenya E. V., Brizhatyuk E. V., Khomyakov V. T. Chastota vozniknoveniya tsistita v zavisimosti ot vida kontratseptsii. Urologiya. 2013; 1: 41–3. (in Russian)]
  7. Неймарк А. И., Шелковикова Н. В. Хронический эндометрит как причина рецидивирующего цистита, осложненного синдромом тазовой боли, у женщин репродуктивного возраста. Акушерство и гинекология. 2011; 4: 34–7. [Neimark A. I., Shelkovikova N. V. Khronicheskii endometrit kak prichina retsidiviruyushchego tsistita, oslozhnennogo sindromom tazovoi boli, u zhenshchin reproduktivnogo vozrasta. Akusherstvo i ginekologiya. 2011; 4: 34–7. (in Russian)]
  8. Бурлев В. А., Дубинская Е. Д. Фенотипические особенности недифференцированных форм дисплазии соединительной ткани у пациенток с тазовыми перитонеальными спайками. Пробл. репродукции. 2012; 2: 8–14. [Burlev V. A., Dubinskaya E. D. Fenotipicheskie osobennosti nedifferentsirovannykh form displazii soedinitel'noi tkani u patsientok s tazovymi peritoneal'nymi spaikami. Probl. reproduktsii. 2012; 2: 8–14. (in Russian)]
  9. Вишневский Е. Л., Лоран О. Б., Саенко В. Е. Симпатическая гиперактивность и резервуарная функция мочевого пузыря у мужчин. Урология. 2010; 5: 57–60. [Vishnevskii E. L., Loran O. B., Saenko V. E. Simpaticheskaya giperaktivnost' i rezervuarnaya funktsiya mochevogo puzyrya u muzhchin. Urologiya. 2010; 5: 57–60. (in Russian)]
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