The Reproductive Vicious Cycle of Obesity: Review of the Literature

Bibliography link: Artymuk N.V., Tachkova O.A., Shurygin S.N. The Reproductive Vicious Cycle of Obesity: Review of the Literature. Doctor.Ru. 2018; 10(154): 22–26. DOI: 10.31550/1727-2378-2018-154-10-22-26
The Reproductive Vicious Cycle of Obesity: Review of the Literature
16 November 09:28

Objective of the Review: To analyze recent publications about the effects of obesity on the reproductive health of women and their offspring.

Key Points: The prevalence of obesity is currently increasing in all countries and all populations. Obesity contributes to complications of pregnancy, labor, and delivery, including pre-eclampsia, gestational diabetes, shoulder dystocia, placental insufficiency, delivery by cesarean section, and asphyxia, as well as fetal death, maternal and early neonatal mortality, and lactation disorders. Children born to obese women have a higher frequency of certain birth defects, macrosomia, hypotrophy, juvenile cerebral palsy, epilepsy, and decreased neuropsychological development. Daughters of obese women often have reproductive disorders and thus become the final stage of a "reproductive vicious cycle." The most significant risk factors for reproductive disorders are eating disorders in adolescence and maternal body mass index at the time of conception.

Conclusion: Preconception maternal lifestyle modifications are the main intervention for prevention of health problems in children. Weight reduction through conservative or surgical treatment is effective in improving perinatal outcomes. Children born to obese women can benefit from regular exercise at any age.

N.V. Artymuk — Kemerovo State Medical University, Russian Ministry of Health. E-mail:

O.A. Tachkova — Kemerovo State Medical University, Russian Ministry of Health. E-mail:

S.N. Shurygin — V.M. Buyanov City Clinical Hospital, Moscow City Department of Health. E-mail:

The Reproductive Vicious Cycle of Obesity: Review of the Literature
16 November 09:28
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