A PEER-REVIEWED JOURNAL OF RESEARCH AND CLINICAL MEDICINEISSN 1727-2378 (Print)         ISSN 2713-2994 (Online)
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Polycystic Ovary Syndrome: Multidisciplinary Issue

For citation: E. E. Grodnitskaya, N. A. Ilina, T. V. Dovzhenko, O. A. Latyshkevich, M. A. Kurtser, G. A. Melnichenko. Polycystic Ovary Syndrome: Multidisciplinary Issue. Doctor.Ru. 2016; 3(120): 59–65.
1 March 00:00

Study Objective: 1) To evaluate the mental and sexual health, psychological well-being, and quality of life of patients with polycystic ovary syndrome (PCOS); and 2) to identify potential associations between the parameters of psychological well-being, specific clinical manifestations (phenotypes) of PCOS, and treatment compliance.

Study Design: This was an overall-population descriptive, analytical study.

Materials and Methods: The study included 96 women of reproductive age who had PCOS, as defined by the European Society of Human Reproduction and Embryology/American Society for Reproductive Medicine criteria. All these women underwent a comprehensive assessment of their psychopathological symptoms, using the MINI-International Neuropsychiatric Interview 6.0 (MINI-6.0), Hospital Anxiety and Depression Scale (HADS), Symptom Checklist 90 ― Revised (SCL-90-R), WHO (Five) Well-Being Index (WHO-5), and Female Sexual Formula (quantification scale).

Study Results: At the time of their participation in the study (mean age, 26.9 ± 4.1), 41.7% of women with PCOS had signs of anxiety and/or depressive disorder (as assessed by MINI-6.0 and HADS), and 34.5% showed a clinically significant reduction in quality of life (as assessed by WHO-5). Signs of sexual disturbances were found in 69.2% of sexually active patients. Signs of psychosocial disturbances were present in 71.6% of participants (as assessed by SCL-90-R). This study showed correlations between the following parameters: the intensity of anxiety and depressive symptoms, the level of psychological distress, quality of life, sexual disturbances, certain social factors, and a clinical picture of PCOS. Patients had been referred to between 2 and 12 gynecologists; and the median follow-up was 8 years. They changed doctors every 2 years. The authors identified specific features of referral pathways in patients with different fenotypes of PCOS.

Conclusion: Promising measures include developing modern guidelines, based on a comprehensive approach to diagnosing and treating PCOS, and providing women with PCOS with educational programs and seminars held at gynecologists' offices with the participation of doctors specialized in other fields.

E. E. Grodnitskaya — Center for Family Planning and Reproduction, Moscow Department of Healthcare. E-mail: elena1778@mail.ru

N. A. Ilina — Moscow Psychiatry Research Institute, Affiliate of the V. P. Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse, Ministry of Health of Russia. E-mail: ilina_nadezhda89@mail.ru

T. V. Dovzhenko — Moscow Psychiatry Research Institute, Affiliate of the V. P. Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse, Ministry of Health of Russia. E-mail: dtv99@mail.ru

O. A. Latyshkevich — Center for Family Planning and Reproduction, Moscow Department of Healthcare. E-mail: sekrGW@cfp.ru

M. A. Kurtser — N. I. Pirogov Russian National Research Medical University, Moscow. E-mail: m.kurtser@mcclinics.ru

G. A. Melnichenko — Scientific Center of Endocrinology, Moscow. I. M. Sechenov First Moscow State Medical University. E-mail: teofrast2000@mail.ru

Доктор.ру
1 March 00:00
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