A PEER-REVIEWED JOURNAL OF RESEARCH AND CLINICAL MEDICINEISSN 1727-2378 (Print)         ISSN 2713-2994 (Online)
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Using Parenteral Nutrition Containing ω3-Fatty Acids for Treatment of Metabolic Disorders in Surgical Patients

For citation: N. G. Arykan, V. V. Stets, V. A. Zyryanov, M. D. Lyubimov, A. E. Shestopalov. Using Parenteral Nutrition Containing ω3-Fatty Acids for Treatment of Metabolic Disorders in Surgical Patients // Doctor.Ru. 2016; 10(127): 51–57.
14 october 2016

Study Objective: To assess the efficacy of postoperative parenteral nutrition (PN) with the SMOFKabiven-central "3 in 1" system in treating metabolic disorders in patients with lower esophagus cancer.

Study Design: This was a prospective controlled comparative randomized study.

Materials and Methods: Patients with tumors of the lower esophagus (43 males aged 67.9 ± 10.5) were divided into two groups, depending on the regimen of PN they received in the postoperative period: Group 1 received Kabiven-central, and Group 2 received SMOFKabiven-central. The duration and the nutritive value of enteral nutrition were the same in both groups.

The efficiency of nutrition support was assessed on Days 1, 3, 5, 7, and 10 after surgery by measuring certain parameters of the protein, fat, and carbohydrate metabolism.

Study Results: Both groups showed unidirectional changes in the metabolic parameters during the period of full parenteral nutrition and the subsequent period of combined parenteral/enteral nutrition. However, in Group 2 these changes occurred more rapidly (on Days 5–7) than in Group 1 (on Day 10).

Conclusion: Because of its high antioxidant content and a unique composition of its fat emulsion, SMOFKabiven can be used as an effective treatment of metabolic disorders in the early postoperative period.

N. G. Arykan — (Volynskaya) Clinical Hospital No. 1, Department of Presidential Affairs of the Russian Federation, Moscow. E-mail: ippv@bk.ru

V. V. Stets — Academician N. N. Burdenko Main Clinical Military Hospital, Ministry of Defense of Russia Moscow. E-mail: stetsv@gmail.com

V. A. Zyryanov — Academician N. N. Burdenko Main Clinical Military Hospital, Ministry of Defense of Russia Moscow. E-mail: stetsv@gmail.com

M. D. Lyubimov — Academician N. N. Burdenko Main Clinical Military Hospital, Ministry of Defense of Russia Moscow. E-mail: stetsv@gmail.com

A. E. Shestopalov — Academician N. N. Burdenko Main Clinical Military Hospital, Ministry of Defense of Russia Moscow. Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia Moscow. E-mail: ashest@yandex.ru

Доктор.ру
14 October 00:00
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