ACADEMIC AND RESEARCH PEER-REVIEWED MEDICAL JOURNALISSN 1727-2378 (Print)         ISSN 2713-2994 (Online)
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Assessing Chances of Successful Implantation in In-Vitro-Fertilization

Bibliography link: E. A. Devyatova, K. A. Tsaturova, E. V. Vartanyan. Assessing Chances of Successful Implantation in In-Vitro-Fertilization // Doctor.Ru. 2016; 7(124): 34–38.
12 September 00:00

Study Objective: To provide the rationale for the use of transvaginal ultrasound with Doppler, as a routine procedure, before embryo transfer (ET) in in-vitro-fertilization (IVF) cycles.

Study Design: This was a retrospective, comparative study.

Materials and Methods: Overall, 101 IVF cycles and ET procedures were performed in this study. In Group 1 (n = 38), blood flow was detected at all levels of uterine vessels. In Group 2 (n = 63), blood flow was absent in spiral arteries (SA). Prior to ET, all patients had transvaginal ultrasound and transvaginal ultrasound with Doppler.

Study Results: Blood flow in SA was detected in 48% of women, aged 20 to 30, and in 27,5% of women, aged 31 to 40 (p = 0.049). Blood flow in SA was absent in 34% of women with known infertility of <5 years and in 87% of women who had been infertile for ≥ 5 years (p = 0.039). The absence of blood flow in SA was significantly more often (р < 0.05) associated with combined infertility (79.5%), unexplained infertility (77.8%), adenomyosis (72.7%), and chronic endometritis (72.7%).

When the endometrial thickness was 8-11 mm, the pregnancy rate after ET was 77.3% in Group 1 and 51.3% in Group 2. This was significantly higher than the pregnancy rate seen in women with other values of endometrial thickness. The group difference was also statistically significant. The overall pregnancy rate after ET was 63.1% in Group 1 and 39.7% in Group 2 (p = 0.045).

Conclusion: Using transvaginal ultrasound with Doppler as a method of endometrial assessment prior to ET in IVF cycles will help reduce the rate of implantation failures and significantly improve IVF outcomes.

E. A. Devyatova — Test-Tube Babies, Clinic of Assisted Reproductive Technologies, Moscow. E-mail: katepillar@mail.ru

K. A. Tsaturova — Test-Tube Babies, Clinic of Assisted Reproductive Technologies, Moscow. E-mail: redaktor@rusmg.ru

E. V. Vartanyan — Test-Tube Babies, Clinic of Assisted Reproductive Technologies, Moscow. Peoples’ Friendship University of Russia, Moscow. E-mail: vartanyan@baby-ivf.ru


Доктор.ру
12 September 00:00
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