ACADEMIC AND RESEARCH PEER-REVIEWED MEDICAL JOURNALISSN 1727-2378 (Print)         ISSN 2713-2994 (Online)
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Squamous Intraepithelial Cervix Lesions: Possible Early Diagnostics and Management

DOI:10.31550/1727-2378-2019-166-11-61-67
Bibliography link: Bairamova G.R., Baranov I.I., Ezhova L.S., Trofimov D.Yu., Priputnevich T.V., Amirkhanyan A.S., Starinskaya A.M. Squamous Intraepithelial Cervix Lesions: Possible Early Diagnostics and Management. Doctor.Ru. 2019; 11(166): 61–67. DOI: 10.31550/1727-2378-2019-166-11-61-67
1 October 16:36

Objective of the Review: to present state-of-the-art data on aetiology, pathogenesis, possibilities of diagnostics, prevention and management of squamous intraepithelial cervix lesions.

Key Points: the review describes the role of human papilloma virus (HPV) in aetiology and pathogenesis of squamous intraepithelial cervix lesions and cervical cancer. Modern methods to diagnose and manage patients with HPV-associated disorders of cervix are presented. We have analysed the results of safety and efficiency studies for combined therapy with Tergynan to treat concomitant cervicitis and vaginitis in squamous intraepithelial cervix lesions; it allows for later adequate assessment of the rate of cervix exposure and avoiding unnecessary aggressive therapy.

Conclusion: selection of an adequate tactics to manage patients with HPV-associated squamous intraepithelial cervix lesions following a comprehensive clinical and laboratory tests makes it possible to prevent unjustified surgeries, it being very important for fertile women planning their pregnancy. Special attention should be paid to concomitant disorders of lower genital organs to ensure timely therapy. A key to successful therapy is adherence to the patient management algorithms in accordance with the national and international recommendations.

G.R. Bairamova — V.I. Kulakov National Medical Scientific Centre of Obstetrics, Gynaecology and Perinatal Medicine of the Ministry of Health of Russia; 4 Academician Oparin St., Moscow, Russian Federation 117997. ELIBRARY.RU SPIN: 3289-5181. Е-mail: bayramova@mail.ru

I.I. Baranov — V.I. Kulakov National Medical Scientific Centre of Obstetrics, Gynaecology and Perinatal Medicine of the Ministry of Health of Russia; 4 Academician Oparin St., Moscow, Russian Federation 117997. ELIBRARY.RU SPIN: 4224-0437. E-mail: i_baranov@oparina4.ru

L.S. Ezhova — V.I. Kulakov National Medical Scientific Centre of Obstetrics, Gynaecology and Perinatal Medicine of the Ministry of Health of Russia; 4 Academician Oparin St., Moscow, Russian Federation 117997. ELIBRARY.RU SPIN: 1397-7517. E-mail: l_ezhova@oparina4.ru

D.Yu. Trofimov — V.I. Kulakov National Medical Scientific Centre of Obstetrics, Gynaecology and Perinatal Medicine of the Ministry of Health of Russia; 4 Academician Oparin St., Moscow, Russian Federation 117997. ELIBRARY.RU SPIN: 3067-2804. E-mail: d.trofimov@dna-tech.ru

T.V. Priputnevich — V.I. Kulakov National Medical Scientific Centre of Obstetrics, Gynaecology and Perinatal Medicine of the Ministry of Health of Russia; 4 Academician Oparin St., Moscow, Russian Federation 117997. ELIBRARY.RU SPIN: 8383-7023. E-mail: priput1@gmail.com

A.S. Amirkhanyan — V.I. Kulakov National Medical Scientific Centre of Obstetrics, Gynaecology and Perinatal Medicine of the Ministry of Health of Russia; 4 Academician Oparin St., Moscow, Russian Federation 117997. Е-mail: 07062005@mail.ru

A.M. Starinskaya — I.M. Sechenov First Moscow State Medical University of the Ministry of Public Health of Russia; 2/4 Bolshaya Pirogovskaya Str., Moscow, Russian Federation 119991. Е-mail: bayramova@mail.ru

Contribution: Bairamova G.R. — data processing, study design, article concepts, approval of the manuscript for publication; Baranov I.I. — review of critically important material, approval of the manuscript for publication; Ezhova L.S. — thematic publications reviewing; Trofimov D.Yu. — review of critically important material; T.V. Priputnevich — review of critically important material; Amirkhanyan A.S. — data processing, article preparation; Starinskaya A.M. — thematic publications reviewing.

The authors declare that they do not have any conflict of interests.

Доктор.ру
1 October 16:36
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