Vitamin D Deficiency and Autoimmune Diseases

Bibliography link: Vitebskaya A. V., Tikhaya M. I. Vitamin D Deficiency and Autoimmune Diseases. Doctor.Ru. 2017; 4(133): 45–48.
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Objective of the Review: To describe the role of vitamin D in the development of autoimmune diseases and its effects on the severity of these conditions.

Key Points: The main function of vitamin D is to regulate calcium and phosphorus metabolism. In 2016 the Global Consensus Recommendations on Prevention and Management of Nutritional Rickets were published, which included diagnostic criteria, based on 25OHD concentrations, for vitamin D deficiency and insufficiency, as well as treatment recommendations.

The discovery of vitamin D’s effects on immune reactions suggested that it might play a role in the pathogenesis of autoimmune diseases. Current studies focus on the role of vitamin D in the development and progression of type 1 diabetes mellitus, multiple sclerosis, asthma, rheumatoid arthritis, and systemic lupus erythematosus.

Conclusion: Studies have shown a relationship between vitamin D levels and the severity of autoimmune disorders, but the effects of vitamin D supplementation on the course of these conditions have not been fully evaluated.

A. V. Vitebskaya — I. M. Sechenov First Moscow State Medical University, Russian Ministry of Health. E-mail:

M. I. Tikhaya — City Pediatric Outpatient Clinic No. 104, Moscow City Department of Health. E-mail:

15 May 00:00
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