A PEER-REVIEWED JOURNAL OF RESEARCH AND CLINICAL MEDICINEISSN 1727-2378 (Print)         ISSN 2713-2994 (Online)
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Cow’s Milk Protein Allergy: Diagnosis and Choice of Formula. Review of Clinical Guidelines

For citation: Namazova-Baranova L. S., Makarova S. G., Novik G. A., Vishneva E. A. Cow’s Milk Protein Allergy: Diagnosis and Choice of Formula. Review of Clinical Guidelines. Doctor.Ru. 2017; 4(133): 61–68.
15 may 2017

Objective of the Paper: To inform a wide range of pediatricians and other specialists about current clinical guidelines on medical care for babies with cow’s milk protein allergy (CMPA).

Key points: Cow’s milk proteins (CMP) are the main clinically significant allergens affecting babies during the first year of life. Early initiation of appropriate treatment significantly improves the prognosis of children with CMPA and prevents the development of more severe allergic disorders later on. The diagnosis of CMPA is based on a careful and complete allergy history. When necessary, a diagnostic diet is administered, with the introduction for diagnostic purposes of a CMP-containing food. Levels of specific IgE antibodies to CMP, and their fractions, as well as skin test parameters, are used as supportive diagnostic markers in the detection of IgE-mediated CMPA and should be interpreted together with clinical data. Complete elimination of foods containing CMP, and of the milk of other animals, for at least 6 months (12 to 18 months in severe cases) is the only effective treatment for CMPA. Babies who are bottle-fed or receive mixed feeding should be given only extensively hydrolyzed milk protein formulas or amino acid-based formulas.

Conclusion: Management protocols provided in current clinical guidelines on CMPA in babies help to achieve successful treatment of this common disorder.

L. S. Namazova-Baranova — National Scientific and Practical Center for Children's Health, Russian Ministry of Health, Moscow. N. I. Pirogov Russian National Research Medical University, Moscow. E-mail: namazova@nczd.ru

S. G. Makarova — National Scientific and Practical Center for Children's Health, Russian Ministry of Health, Moscow. E-mail: sm27@yandex.ru

G. A. Novik — St. Petersburg State Pediatric Medical University, Russian Ministry of Health. E-mail: ga_novik@mail.ru

E. A. Vishneva — National Scientific and Practical Center for Children's Health, Russian Ministry of Health, Moscow. E-mail: vishneva@nzsd.ru

Доктор.ру
15 May 00:00
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