Objective of the Paper: To demonstrate a case of successful use of tocilizumab in a child with systemic juvenile idiopathic arthritis (JIA).
Key Points. A clinical variant of JIA is systemic arthritis (systemic JIA). Currently, management of systemic JIA includes tocilizumab, a recombinant humanised anti–interleukin-6 receptor monoclonal antibody. The article describes a case of successful use of tocilizumab in a child with systemic JIA after inefficient therapy with glucocorticosteroids and methotrexate.
Conclusion. Systemic JIA is the severest clinical JIA variant. Tocilizumab allows achieving the quiescent disease stage where the standard therapy with glucocorticosteroids and methotrexate is ineffective.
Contributions: Aksenov, A.V. — thematic publications reviewing, manuscript preparation; Ivanovskaya, E.A. — patient management in Rheumatology Unit.
Conflict of interest: The authors declare that they do not have any conflict of interests.
A.V. Aksenov (Corresponding author) — South Ural State Medical University of the Ministry of Health of the Russian Federation; 64 Vorovskiy Str., Chelyabinsk, Russian Federation 454092. E-mail: firstname.lastname@example.org
E.A. Ivanovskaya — Children's City Clinical Hospital No.8; 2 Druzhby Str., Chelyabinsk, Russian Federation 454047. E-mail: Ivanovskava.Elena@yandex.ru
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