The Role of Calcium and Vitamin D3 in the Repair of Fractured Bones

For citation: Luneva S.N., Matveeva E.L., Gasanova A.G., Boichuk S.P., Sazonova N.V. The Role of Calcium and Vitamin D3 in the Repair of Fractured Bones. Doctor.Ru. 2019; 2(157): 55­60. DOI: 10.31550/1727-2378-2019-157-2-55-60
5 March 17:17

Objective of the Review: To provide a systematic overview of the literature on the role of calcium and vitamin D in the repair of fractured bones.

Key Points: Calcium and vitamin D deficiencies are the key risk factors for osteoporosis. Because calcium is essential for fracture callus mineralization, bone repair is often compromised in patients with osteoporosis. Clinical data suggest that fractures, especially osteoporotic fractures, may cause post-traumatic loss of bone tissue, resulting in increased risk of secondary fractures. There are only limited studies, however, of the role of calcium and vitamin D in bone repair and post-traumatic metabolism in fractured bones.

Conclusion: Consumption of adequate amounts of calcium and vitamin D is important for patients with fractures. Calcium and vitamin D supplements or combination preparations may be considered the main treatment for fractures in older patients, who are usually deficient in both nutrients.

The authors declare that they do not have any conflict of interests.

S.N. LunevaAcademician G.A. Ilizarov Russian Scientific Center for Restorative Traumatology and Orthopedics, Russian Ministry of Health, 6 Marii Ulyanovoy St., Kurgan, Russian Federation 640014. E-mail:

E.L. MatveevaAcademician G.A. Ilizarov Russian Scientific Center for Restorative Traumatology and Orthopedics, Russian Ministry of Health, 6 Marii Ulyanovoy St., Kurgan, Russian Federation 640014. E-mail:

A.G. Gasanova Academician G.A. Ilizarov Russian Scientific Center for Restorative Traumatology and Orthopedics, Russian Ministry of Health, 6 Marii Ulyanovoy St., Kurgan, Russian Federation 640014. E-mail:

S.P. BoichukAcademician G.A. Ilizarov Russian Scientific Center for Restorative Traumatology and Orthopedics, Russian Ministry of Health, 6 Marii Ulyanovoy St., Kurgan, Russian Federation 640014. E-mail:

N.V. SazonovaAcademician G.A. Ilizarov Russian Scientific Center for Restorative Traumatology and Orthopedics, Russian Ministry of Health, 6 Marii Ulyanovoy St., Kurgan, Russian Federation 640014. E-mail:

5 March 17:17
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