Ventilator-Associated Pneumonia: Review of Case-History Data of Patients Who Died of Myocardial Infarction or Cerebrovascular Accidents

Bibliography link: D. V. Odintsova, A. G. Malyavin, O. V. Zairatiants. Ventilator-Associated Pneumonia: Review of Case-History Data of Patients Who Died of Myocardial Infarction or Cerebrovascular Accidents. Doctor.Ru. 2016; 2(119): 48–51.
12 February 00:00

Study Objective: To evaluate the incidence of nosocomial ventilator-associated pneumonia (VAP) in patients who died of myocardial infarction or cerebrovascular accidents.

Materials and Methods: We reviewed archive data of 140 autopsy reports and case histories of patients who died of cardiovascular accidents. Of these 140 patients, mechanical ventilation (MV) was used in 83 (59.3%) people. Depending on the risk of nosocomial VAP, these patients were divided into two groups: 32 (22.9%) patients who had been on ventilator support for less than 3 days, and 51 (36.4%) patients who had been on MV for 3 days or longer.

Study Results: Of the 83 patients on MV, 57 (68.7%) developed pneumonia. Nosocomial VAP developed significantly more often in patients who had been on MV for 3 days or longer. In this group of patients, the probability of nosocomial VAP was 4.473-fold higher (95% confidence interval: 1.815–11.024) than in those who were not put on MV or had been on MV for less than 3 days.

Conclusion: This study confirmed that nosocomial VAP is a common condition in patients with cardiovascular accidents. It is related to the length of mechanical support. Creation of treatment and management guidelines for this patient population would improve their survival and prognosis.

D. V. Odintsova — A. I. Evdokimov Moscow State University of Medicine and Dentistry. E-mail:

A. G. Malyavin — A. I. Evdokimov Moscow State University of Medicine and Dentistry. E-mail:

O. V. Zairatiants — A. I. Evdokimov Moscow State University of Medicine and Dentistry. E-mail:

12 February 00:00
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